Antidepressant Medications : Rules for Pilots

FAA Policies on Pharmaceuticals for Airmen

Apr 2014

Guidance is compiled and interpreted by professional pilots and physicians at from the 2014 AME Guide, FAA and FDA web data ( &, instructions specified in the Aeronautical Information Manual, Federal Air Surgeon Bulletins from 1999-2015, and 14 CFR Part 61 and Part 67 (the FARs).


  1. Code of Federal Regulations for Airmen
    • First-Class Airman Medical Certificate: 67.107
    • Second-Class Airman Medical Certificate: 67.207
    • Third-Class Airman Medical Certificate: 67.307
  2. Medical History
  3. Aeromedical Decision Considerations
  4. Protocol: See Aerospace Medical Dispositions, Item 47. Psychiatric Conditions
  5. Pharmaceutical Considerations: The use of a psychotropic drug is disqualifying for aeromedical certification purposes - this includes all antidepressant drugs including selective serotonin reuptake inhibitors (SSRIs). However, the FAA has determined that airmen requesting first, second, or third class medical certificates while being treated with one of four specific SSRIs may be considered (see Use of Antidepressant Medications). The Authorization decision is made on a case by case basis. The AME may not issue.

Summary: This page reviewed the medical and legal aviation aspects of Antidepressant Medications compiled from recent FAA and FDA reports.

This page discussed Antidepressant Medications : Rules for Pilots

Reminder: use to familiarize yourself with aviation medical regulations and guidelines, but always discuss your specific situation with one or more AMEs before dedicating resources toward expensive clinical workups. Find an AME now