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Blood Pressure Medication Requirements for Pilots
FAA Rules for Hypertension Medications
  1. Code of Federal Regulations (Legal Extract)

  2. Medical History: Item 18.h., High or low blood pressure.
    The applicant should provide history and treatment, type of medication, purpose, and duration of use. Issuance of a medical certificate is dependant on current blood pressure levels and whether the applicant is taking anti-hypertensive medication. The AME should also determine if the applicant has a history of complications, adverse reactions to therapy, hospitalization, etc.

  3. Aeromedical Decision Considerations:

  4. Protocol: N/A. See Hypertension Worksheet.

Acceptable HTN Medication Options
(when other certification criteria are met)
Alpha adrenergic blockers Calcium channel blockers
Angiotensin converting enzyme (ACE) inhibitors  Direct renin inhibitors
Angiotensin II receptor antagonists (ARBs) Direct vasodilators
Beta-adrenergic blockers Diuretics
  • Seven-day (7) no fly/ground trial is required when starting a new hypertension (HTN) medication to verify no side effects.
  • AME should issue (if otherwise qualified) if the airmen is on 3 or fewer medications.
  • Uses of beta-adrenergic blockers ARE allowed with insulin, meglitinides, or sulfonylureas.
UNACCEPTABLE HTN Medications
(as a single agent or in any combination product)
Clonidine (ex. Catapres/Clorpres)
Guanabenz
Guanfacine/Tenex
Methyldopa
Nitrates (ex. nitroglycerin/isosorbide dinitrate/isosorbide mononitrate)
Reserpine
AME Instruction: DO NOT ISSUE Medical Certificate for pilots on these medications
FAA AME Guide Dec 2025 version