AME Guidance for Thrombocytopenia (Low Platelet Count)

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AME Guidance for Processing a Special Issuance Renewal Request (AASI)

The FAA describes an AME Assisted Special Issuance (AASI) as a process that provides Examiners the ability to re-issue an airman medical certificate under the provisions of an Authorization for Special Issuance of a Medical Certificate (Authorization) to an applicant who has a medical condition that is disqualifying under Title 14 of the Code of Federal Regulations (14 CFR) part 67.

An FAA physician who is an FAA staff member (higher in the chain of command than your AME) provides the initial certification decision and grants the Authorization in accordance with 14 CFR § 67.401. The FAA's initial Authorization letter is accompanied by attachments that specify the information that treating physician(s) must provide for the re-issuance determination. The treating physicians are not typically your AME, but are more likely to be specialists in the problem area or your primary care provider.

If this is a first-time application for an AASI for Thrombocytopenia, and the applicant has all the requisite medical information necessary for a determination, the AME must defer and submit all of the documentation to the AMCD or the Regional Flight Surgeon for the initial determination.

Examiners may re-issue an airman medical certificate for Thrombocytopenia under the provisions of an Authorization, if the applicant provides the following:

  • An Authorization granted by the FAA; and
  • An update of the status of the disease from the last FAA medical examination and any testing deemed necessary by the treating physician; and
  • CBC within the past 90 days.
The AME must defer to the AMCD or Region if:
  • There has been any recurrence or disease progression; or
  • There has been any bleeding that required treatment; or
  • Any new treatment is initiated such as IVIG, high dose steroids, platelet transfusion, splenectomy (as treatment, not traumatic), or others; or
  • Platelet count falls below 50,000/microL
FAA AME Guide Dec 2025 version
Dec 27, 2025
Dec 27, 2025