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AME Guidance for Processing a CLL-SLL CACI (Condition AME Can Issue)

Conditions AMEs Can Issue (CACI) are a series of conditions which allow AMEs to regular issue the pilot medical certificate if the applicant meets the parameters of the CACI Condition Worksheet. The worksheets provide detailed instructions to the examiner and outline condition-specific requirements for the applicant.

  • AME must review the disposition table BEFORE the CACI worksheet to verify a CACI is required.
  • If all the CACI criteria are met and the applicant is otherwise qualified, the AME may issue on the first exam or the first time the condition is reported to the AME without contacting AMCD/RFS. Document the appropriate notes in Block 60 and keep the supporting documents in your files; they do not need to be submitted to the FAA at this time.
  • If the requirements are not met, the AME must defer the exam and send the supporting documents to the FAA.

To determine the applicant's eligibility for certification, the AME must review a current, detailed Clinical Progress Note generated from a clinic visit with the treating physician or specialist no more than 90 days prior to the AME exam. If the applicant meets ALL the acceptable certification criteria listed below, the Examiner can issue. Applicants for first- or second-class must provide this information annually; applicants for third-class must provide the information with each required exam.

AME MUST REVIEW ACCEPTABLE CERTIFICATION CRITERIA
Treating Oncologist finds the condition stable and
  • Asymptomatic
  • Recommends observation only
  • Monitored for 5 or more years
[ ] Yes
Age at diagnosis [ ] 40 or older
Rai stage 0 - 1 and/or Binet stage A [ ] Yes
Applicant has NO evidence of active disease.*

(Consider iwCLL criteria.)

*Examples of active disease include weight loss (unintentional) greater than 10 pounds; new palpable lymph nodes
[ ] Yes
Lab(s) within the past 90 days show:
  • Hemoglobin > = 11 mg/dL
  • Platelets > = 100,000/microL
  • Total or absolute lymphocyte count doubling time is greater than 6 months
[ ] Yes

AME MUST NOTE in Block 60 one of the following:

Applicants with CLL:

[ ] CACI qualified CLL.

[ ] Has current OR previous SI/AASI but now CACI qualified CLL.

[ ] NOT CACI qualified CLL. I have deferred. (Submit supporting documents.)

Applicants with SLL:

[ ] CACI qualified SLL

[ ] Has current OR previous SI/AASI but now CACI qualified SLL.

[ ] NOT CACI qualified SLL. I have deferred. (Submit supporting documents.)

FAA AME Guide Dec 2025 version
Nov 24, 2021
Dec 29, 2025
Dec 29, 2025