| Generally Safe to Fly (GO) | Avoid (NO GO) |
|---|---|
|
FAA states almost all are allowed: • Anti-fungal topical • Antipruritics • Topical corticosteroid |
No banned topical agents listed in AME Guide as of Jan 2026 |
Itchy (pruritic) rash can be distracting, and orally ingested system meds (pills, tablets or capsules) antihistamines are problematic for aviators. Injectable anti-itch medications are not compatible with flight. You are safe with topicals - even topicals with corticosteroids like cortisone. Think twice before taking oral antihistamines because the most effective anti-itch ones like benadryl and diphenhydramine are not safe in flight. As always The FAA cautions: that you as the pilot in command must ensure the underlying condition is not an issue with safe flight.
Disclaimer: Neither the FAA nor FlightPhysical.com will attempt to publish all-inclusive references. Online guidance does not replace medical advice from your PCP and/or AME. Most doctors are not AMEs, and your regular Primary Care Provider (PCP) or specialist will know more about you and/or your specific medical condition than an AME, but is probably untrained or unfamiliar with aviation medicine. Follow 14 CFR 61.53 (duty to self-ground when ill) for your safety and that of your passengers. Don't fly after taking a new medication for the first time until 48 hours have past without side effects.
When in doubt - DO NOT FLY.
FAA and MayoClinic
See related content on Antihistamine Page